Anti-GNB2L1 antibody produced in rabbit

产品说明

一般描述

Guanine nucleotide binding protein (G protein), β polypeptide 2-like 1 (GNB2L1) is a stable housekeeping gene expressed in alveolar macrophage and neutrophils. The gene has been hypothesized to encode a protein RACK1 (Receptor for activated C kinase 1). It is mapped on the telomeric position of chromosome 5q35.3.

特异性

Anti-GNB2L1 polyclonal antibody reacts with canine, human, mouse, rat, pig, zebrafish, and chicken guanine nucleotide binding protein (G protein), β polypeptide 2-like 1 proteins.

免疫原

Synthetic peptide directed towards the C terminal region of human GNB2L1

应用

Anti-GNB2L1 polyclonal antibody is used to tag guanine nucleotide binding protein (G protein), β polypeptide 2-like 1 protein for detection and quantitation by Western blotting and in cells and tissues by immunohistochemical (IHC) techniques. It is used as a probe to study the expression of guanine nucleotide binding protein (G protein), β polypeptide 2-like 1 in macrophages and neutrophils.

生化/生理作用

Guanine nucleotide binding protein (G protein), β polypeptide 2-like 1 (GNB2L1) is a scaffold protein highly involved in the binding and anchorage of protein kinase C. It has been hypothesized that GNB2L1 may act as a regulatory cofactor of multidrug resistance protein 3 (MDR3/ABCB4) and is vital for the plasma membrane localization and for mediating the translocation function of ABCB4.

序列

Synthetic peptide located within the following region: LEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVW

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

产品性质

安全信息