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Anti-ERCC8 (ab2) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV32149
规格纯度
affinity isolated antibody
参考价格
6305.78 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

ERCC8 is a WD repeat protein that has been implicated in Cockayne syndrome. Cockayne syndrome is an autosomal recessive disorder that is characterized by mental retardation, photosensitivity, neurodegeneration and premature death.
Rabbit Anti-ERCC8 recognizes canine, zebrafish, chicken, human, and mouse ERCC8.

免疫原

Synthetic peptide directed towards the N terminal region of human ERCC8

应用

Rabbit Anti-ERCC8 can be used for western blot application at a concentration of 0.5μg/ml.

生化/生理作用

ERCC8 is a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes.

序列

Synthetic peptide located within the following region: DVERIHGGGINTLDIEPVEGRYMLSGGSDGVIVLYDLENSSRQSYYTCKA

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 44 kDa
species reactivityhuman
浓度0.5 mg - 1 mg/mL
technique(s)immunohistochemistry: suitable
western blot: suitable
NCBI登记号NP_000073
UniProt登记号Q13216
运输wet ice
储存温度−20℃
Gene Informationhuman ... ERCC8(1161)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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