产品说明
一般描述
EPLIN (epithelial protein lost in neoplasm or Lima-1) is known to interact with actin and couples with α-catenin. This subsequently facilitates the association of cadherin-catenin complex to F-actin stabilizing actin fibres and forming the adhesion belt. EPLIN also increases the quantity of actin stress fibers and blocks Rac-induced membrane ruffling.
Rabbit Anti-EPLIN antibody recognizes canine, bovine, pig, mouse, and human EPLIN.
免疫原
Synthetic peptide directed towards the middle region of Human LIMA1
应用
Rabbit Anti-EPLIN antibody is suitable for western blot applications at a concentration of 2.0 μg/ml.
生化/生理作用
This gene encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. It is downregulated in some cancer cell lines. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and expression of some of the variants maybe independently regulated.
序列
Synthetic peptide located within the following region: GVLAASMEAKASSQQEKEDKPAETKKLRIAWPPPTELGSSGSALEEGIKM
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD04118453 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 85 kDa |
| species reactivity | bovine, human |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_001107018 |
| UniProt登记号 | Q9UHB6 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... EPLIN(51474) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
