产品说明
一般描述
Developmentally regulated RNA-binding protein 1 (DRBP1) is an inducible protein that binds to RNA stability elements (AU-rich elements) in the 3′-untranlated region of fragile mRNAs that appear to be essential for cell (cardiomyocytes) survival during ischemic/hypoxic stress.
特异性
Anti-DRB1 polyclonal antibody reacts with human, mouse, rat, bovine, and canine developmentally regulated RNA-binding protein 1 proteins.
免疫原
Synthetic peptide directed towards the N terminal region of human DRB1
应用
Anti-DRB1 polyclonal antibody is used to tag developmentally regulated RNA-binding protein 1 proteins for detection and quantitation by Western blotting and in cells and tissues by immunohistochemical (IHC) techniques. It is used as a probe to study the role of Developmentally regulated RNA-binding protein 1 proteins in cell, cardiomyocyte, survival at the level of survival gene mRNA stabilization.
生化/生理作用
DRB1 is RNA-binding protein with binding specificity for poly(C) and may play an important role in neural development.
序列
Synthetic peptide located within the following region: MDEAGSSASGGGFRPGVDSLDEPPNSRIFLVISKYTPESVLRERFSPFGD
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 36 kDa |
| species reactivity | guinea pig, mouse, rabbit, dog, rat, human |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_694453 |
| UniProt登记号 | Q8IUH3-3 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... DRB1(129831) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
