位置:首页 > 品牌 > Sigma-Aldrich >

Anti-DIDO1 (AB2) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV39543
规格纯度
affinity isolated antibody
参考价格
6305.78 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Death inducer-obliterator 1 (DIDO1) is known to be a BMP-target gene and is involved in melanoma progression. It has also been implicated in colorectal carcinogenesis.
Rabbit Anti-DIDO1 antibody recognizes chicken, bovine, human, mouse, rat, and canine DIDO1.

免疫原

Synthetic peptide directed towards the N terminal region of human DIDO1

应用

Rabbit Anti-DIDO1 (AB2) antibody is suitable for western blot applications at a concentration of 0.5 μg/ml.

生化/生理作用

In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. DIDO1 gene is similar to the mouse gene and therefore is thought to be involved in apoptosis.Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. This gene is similar to the mouse gene and therefore is thought to be involved in apoptosis. Alternatively spliced transcripts have been found for this gene, encoding multiple isoforms.Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. This gene is similar to the mouse gene and therefore is thought to be involved in apoptosis. Alternatively spliced transcripts have been found for this gene, encoding multiple isoforms.

序列

Synthetic peptide located within the following region: MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEP

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 61 kDa
species reactivityhorse, human, mouse, dog, bovine, guinea pig, rabbit, rat
浓度0.5 mg - 1 mg/mL
technique(s)western blot: suitable
NCBI登记号NP_071388
UniProt登记号Q9BTC0-3
运输wet ice
储存温度−20℃
Gene Informationhuman ... DIDO1(11083)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

推荐产品
| 首页 | 联系我们 | 会员服务 | 广告服务 | 友情链接 |
版权所有 CopyRight © 2008-2024 粤ICP备08119708号