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Anti-DFFA antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4500644
规格纯度
affinity isolated antibody
参考价格
4618.16 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

DFFA (DNA fragmentation factor, α polypeptide) is a heterodimeric 45kDa protein mapped on chromosome location 1p36.2-36.3. It is localized to the chromatin fraction under both the conditions, apoptotic and non-apoptotic state. Its expression also has been found in neuroblastoma (NB) cell lines.
Anti-DFFA Antibody detects endogenous levels of total DFFA protein.

免疫原

The antiserum was produced against synthesized peptide derived from human DFFA.

Immunogen Range: 151-200

应用

Anti-DFFA antibody produced in rabbit is suitable for western blot and immunohistochemistry studies.

生化/生理作用

DFFA (DNA fragmentation factor, α polypeptide) functions as a chaperone of DNA fragmentation factor 40 (DFF40) in apoptosis and balancing genomic stability. The activity of DFF is induced by cleavage of DFFA by caspase-3, resulting in release of DFF40, which degrades chromosomal DNA. During menstruation, the apoptosis of endometrium cells is associated with DFFA activation. DFFA expression decreases after menopause. DFFA is a target of miR-145.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD02096208
NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen 36 kDa
species reactivitymouse, human, rat
浓度~1 mg/mL
technique(s)ELISA: 1:20000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登记号O00273
UniProt登记号O00273
运输wet ice
储存温度−20℃
Gene Informationhuman ... DFFA(1676)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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