产品说明
一般描述
DEK is a non-histone nuclear phosphoprotein that regulates hematopoiesis. It is secreted by certain cells in exosomes or in free form and regulates the global heterochromatin integrity.
免疫原
Synthetic peptide directed towards the N terminal region of human DEK
应用
Anti-DEK antibody produced in rabbit is suitable for western blotting at a concentration of 1.25 μg/ml.
生化/生理作用
DEK functions as a nuclear protein and also as a secreted molecule. When secreted it acts in a paracrine fashion to regulate the transcription factor C/EBPα for myeloid cell differentiation. High levels of DEK have been observed in a variety of cancers making it an important prognostic and tumor progression marker.
序列
Synthetic peptide located within the following region: AAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEG
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
偶联物 | unconjugated |
抗体形式 | IgG fraction of antiserum |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | 43 kDa |
species reactivity | human |
浓度 | 0.5 mg - 1 mg/mL |
technique(s) | western blot: suitable |
NCBI登记号 | NP_001128181 |
UniProt登记号 | P35659 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... DEK(7913) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |