产品说明
一般描述
Cyclins are key regulatory proteins that control cell cycle progression by phosphorylating cyclin-dependent kinases.
免疫原
Synthetic peptide directed towards the C terminal region of human CCNH
应用
Anti- CCNH antibody produced in rabbit is suitable for western blotting at a concentration of 1 μg/ml. For immunohistochemistry of paraffin-embedded tissue sections, a concentration of 4-8 μg/ml is suitable.
生化/生理作用
Cyclin H associates with cyclin-dependent kinase7 (Cdk7) and the complex regulates RNA polymerase in several species. It regulates the transcription machinery required for larval development of zebrafish. In Arabidopsis, CCNH is essential in drought stress responses independent of cyclin dependent kinase D. The expression of CCNH is increased in humans with gastrointestinal stromal tumors.
序列
Synthetic peptide located within the following region: KQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 38 kDa |
| species reactivity | human, guinea pig, horse |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI登记号 | NP_001230 |
| UniProt登记号 | P51946 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... CCNH(902) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
