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ANTI-ASB10(N-TERMINAL) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB1306844
规格纯度
affinity isolated antibody, buffered aqueous solution
参考价格
6098.42 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

ASB10 belongs to the ankyrin repeat and SOCS box (ASB) family and the suppressor of cytokine signaling (SOCS) box protein superfamily. It consists of a number of ankyrin (ANK) repeat protein domains and a C-terminal suppressor of cytokine signaling (SOCS) box. Depending on the number of ankyrin (ANK) repeat protein domains, ASB family is divided into 1-18 types. ASB10 is composed of seven ANK repeat domains and a SOCS box at the C-terminus end.

应用

ANTI-ASB10(N-TERMINAL) antibody produced in rabbit is suitable for western blot at a dilution of 1:1000.

生化/生理作用

ASB10 (ankyrin repeat and SOCS box containing 10) plays a vital role in the ubiquitination-mediated proteasomal and autophagy-lysosomal degradation pathways. The ANK repeat containing domain is responsible for protein-protein interactions whereas the SOCS (suppressor of cytokine signaling) box motif helps in ubiquitination of the protein by binding to the multisubunit E3 ubiquitin ligase complex. ASB family interacts specifically with Cul5-Rbx2 in cells to form an E3 ubiquitin (Ub) ligase complex.

外形

Supplied in PBS with 0.09% (W/V) sodium azide

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 50894 Da
species reactivityhuman
technique(s)western blot: 1:1000
NCBI登记号NP_001135931.2
UniProt登记号Q8WXI3
运输wet ice
储存温度−20℃
Gene Informationhuman ... ASB10(136371)

安全信息

储存分类代码12 - Non Combustible Liquids
闪点(F)Not applicable
闪点(C)Not applicable

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