产品说明
一般描述
Neurogenin 3 (NEUROG3) is also termed as Ngn3. This protein belongs to the subfamily of basic-helix-loop-helix (bHLH) transcription factors. It is located on human chromosome 10q.
Neurogenin-3 (NEUROG3) is expressed in endocrine progenitor cells and is required for endocrine cell development in the pancreas and intestine (Wang et al., 2006 [PubMed 16855267]). It belongs to a family of basic helix-loop-helix transcription factors involved in the determination of neural precursor cells in the neuroectoderm (Gradwohl et al., 2000 [PubMed 10677506]).[supplied by OMIM]
免疫原
NEUROG3 (NP_066279, 1 a.a. ~ 101 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MTPQPSGAPTVQVTRETERSFPRASEDEVTCPTSAPPSPTRTRGNCAEAEEGGCRGAPRKLRARRGGRSRPKSELALSKQRRSRRKKANDRERNRMHNLN*
生化/生理作用
Neurogenin 3 (NEUROG3) is required for all intestinal enteroendocrine cells. It participates in the differentiation of endocrine pancreas. This protein is also essential to induce islet cell maturation and to maintain islet function.
外形
Solution in phosphate buffered saline, pH 7.4
法律信息
GenBank is a registered trademark of United States Department of Health and Human Services
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD01633905 |
| NACRES | NA.41 |
产品性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | 4B7, monoclonal |
| 形式 | buffered aqueous solution |
| species reactivity | human |
| technique(s) | immunofluorescence: suitable immunoprecipitation (IP): suitable indirect ELISA: suitable western blot: 1-5 μg/mL |
| 同位素/亚型 | IgG2bκ |
| GenBank® accession no. | NM_020999 |
| UniProt登记号 | Q9Y4Z2 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... NEUROG3(50674) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
