产品说明
免疫原
Recombinant human FEN-1 protein encoding amino acids 1-380 purified E. coli.
应用
Suggested starting dilutions are as follows: ICC/IF: Assay-dependent dilution, IP: Assay-dependent dilution, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
生化/生理作用
FEN-1 (Flap Endonuclease and Five prime Exonuclease) is a 42 a protein that functions as an endonuclease that cleaves branched DNA structures containing single-stranded 5′ flaps or as an exonuclease on DNA nicks and gaps. FEN-1 endonuclease and exonuclease activities are stimulated by an association with proliferating cell nuclear antigen (PCNA) in the nucleus. FEN-1 is believed to have important roles in DNA replication and repair and is required in cell-free DNA replication systems.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Phosphate-buffered saline, no preservative added.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
产品性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | 4E7 monoclonal |
| 形式 | liquid |
| 分子量 | 42 kDa |
| species reactivity | human, mouse |
| 浓度 | 1 mg/mL |
| technique(s) | immunocytochemistry: suitable immunofluorescence: suitable immunoprecipitation (IP): suitable western blot: 500-3000 |
| 同位素/亚型 | IgG1 |
| UniProt登记号 | P39748 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... FEN1(2237) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
