产品说明
免疫原
Human FANCD2 fusion protein
应用
For WB: Use at an assay dependent dilution. Predicted molecular weight: 28 kDa. Optimal dilutions/concentrations should be determined by the researcher.
生化/生理作用
Fanconi Anemia Complementation Group D2 (FANCD2) protein is one of at least six factors shown to be involved in the autosomal-recessive cancer-prone disorder, Fanconi Anemia (FA). FA group D has been shown to be comprised of two separate proteins, FANCD1 and FANCD2. Mutations in BRCA2 can cause FANCD1. FANCD2 has been shown to colocalize with BRCA1 in ionizing radiation-induced foci. FANCD2 is involved in genomic resistance to DNA cross-linking reagents, and the arrest of DNA synthesis following exposure to ionizing radiation. FANCD2 has been shown to directly interact with NBS1
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
其他说明
Purification: Protein G affinity purified
外形
Phosphate-buffered saline, pH 7.2, contaning no preservatives
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
产品性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | 6, monoclonal |
| 形式 | buffered aqueous solution |
| species reactivity | human |
| 浓度 | 1mg/mL |
| technique(s) | western blot: suitable |
| 同位素/亚型 | IgG |
| UniProt登记号 | Q9BXW9 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... FANCD2(2177) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
