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Monoclonal Anti-CD107a-PE antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB4700418
规格纯度
clone H4A3, purified immunoglobulin, buffered aqueous solution
参考价格
5190.27 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

CD107a (lysosome-associated membrane protein-1, LAMP-1), together with LAMP-2, is a major constituent of lysosomal membrane, 1-2% of total CD107a is found also on the plasma membrane. The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes. Increased CD107a immunoreactivity is observed in neurons, and in glial cells surrounding senile plaques in Alzheimer′s disease cases and is localized mainly in medullary epithelial cells, single macrophages and lymphocytes in acute thymic involution. CD107a is a good marker of mast cell activation.

特异性

The antibody H4A3 recognizes CD107a, a 100-120 kDa glycoprotein expressed mainly on lysosomal, but also on the plasma membrane.

免疫原

Human PBMC

应用

The reagent is designed for Flow Cytometry analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 1e6 cells in a suspension. The content of a vial (0.4 mL) is sufficient for 100 tests.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Solution in phosphate buffered saline containing 15 mM sodium azide and 0.2% high-grade protease free BSA as a stabilizing agent.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

产品性质

质量水平100
生物来源mouse
偶联物phycoerythrin (R-PE) conjugate
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆H4A3, monoclonal
形式buffered aqueous solution
species reactivitynonhuman primates, human, mouse
technique(s)flow cytometry: suitable
同位素/亚型IgG1
NCBI登记号NM_005561.3
UniProt登记号P11279
运输wet ice
储存温度2-8℃
Gene Informationhuman ... LAMP1(3916)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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