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Monoclonal Anti-CALCA antibody produced in mouse

品牌
Sigma-Aldrich
货号
WH0000796M1
规格纯度
clone 4B10, purified immunoglobulin, buffered aqueous solution
参考价格
4474.51 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

The calcitonin related polypeptide α (CALCA) gene contains five exons and spans over a length of approximately 3.8 kb. It is mapped to human chromosome 11p15.2-p15.1. The gene codes for a 37-amino-acid vasoactive neuropeptide. In mammals, CALCA is expressed in the central and peripheral nervous systems.
Calcitonin is a peptide hormone synthesized by the parafollicular cells of the thyroid. It causes reduction in serum calcium, an effect opposite to that of parathyroid hormone (PTH; MIM 168450).

免疫原

CALCA (NP_001732, 52 a.a. ~ 141 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
AALVQDYVQMKASELEQEQEREGSSLDSPRSKRCGNLSTCMLGTYTQDFNKFHTFPQTAIGVGAPGKKRDMSSDLERDHRPHVSMPQNAN

生化/生理作用

Calcitonin related polypeptide α (CALCA) acts as a potent vasodilator. This protein also has an essential role in placental angiogenesis and fetal growth. CALCA is involved in the regulation of bone calcium metabolism. Mutation in the gene might be associated with the risk of susceptibility to Parkinson′s disease, ovarian cancer and essential hypertension (EH).

外形

Solution in phosphate buffered saline, pH 7.4

法律信息

GenBank is a registered trademark of United States Department of Health and Human Services

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD00162202
NACRESNA.41

产品性质

质量水平100
生物来源mouse
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆4B10, monoclonal
形式buffered aqueous solution
species reactivityhuman
technique(s)indirect ELISA: suitable
western blot: 1-5 μg/mL
同位素/亚型IgG2aκ
GenBank® accession no.NM_001741
UniProt登记号P01258
运输dry ice
储存温度−20℃
Gene Informationhuman ... CALCA(796)

安全信息

储存分类代码12 - Non Combustible Liquids
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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