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tert-Butyl 1-oxa-4,9-diazaspiro[5.6]dodecane-9-carboxylate

品牌
Sigma-Aldrich
CAS
1779375-54-0
货号
920541
包装型号
规格纯度
参考价格
4357.97 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

tert-Butyl 1-oxa-4,9-diazaspiro[5.6]dodecane-9-carboxylate is useful as a rigid linker in PROTAC development for targeted protein degradation as well as chemical conjugates. Incorporation of rigidity into the linker region of bifunctional protein degraders may impact the 3D orientation of the degrader and thus ternary complex formation as well as optimization of drug-like properties. Developed in partnership with ComInnex.

Similar to CH4979588668

其他说明

Portal: Building PROTAC® Degraders for Targeted Protein Degradation

Crosslinkers for Bioconjugation

Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation

法律信息

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

基本信息

经验(实验)分子式C14H26N2O3
分子量270.37
MDL编号MFCD22396643

产品性质

质量水平100
形式solid
储存温度2-8℃
SMILES stringCC(C)(OC(N1CCCC2(CC1)CNCCO2)=O)C

Sigma-Aldrich

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