产品说明
应用
t-Boc-N-amido-PEG2-CH2CO2H is a heterobifunctional, PEGylated crosslinker featuring a Boc-protected amine at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. t-Boc-N-amido-PEG2-CH2CO2H can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.
This is a crosslinker with a t-Boc protected amine on one end and a carboxyl group on the other end. The compound contains two PEG units to help improve solubility.
法律信息
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
基本信息
| 经验(实验)分子式 | C11H21NO6 |
| 分子量 | 263.29 |
| MDL编号 | MFCD17019374 |
产品性质
| 测定 | ≥95% |
| 形式 | liquid |
| 密度 | 1.15 g/cm3 (lit.) |
| 储存温度 | −20℃ |
| SMILES string | OC(COCCOCCNC(OC(C)(C)C)=O)=O |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
