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SILuTMProt B2M beta-2-microglobulin human

品牌
Sigma-Aldrich
货号
MSST0015
规格纯度
recombinant, expressed in HEK 293 cells, SIL MS Protein Standard, 13C- and 15N-labeled
参考价格
11120.3 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

SILu Prot B2M is a recombinant, stable isotope-labeled human B2M which incorporates [13C6, 15N4]-Arginine and [13C6, 15N2]-Lysine. Expressed in human 293 cells, it is designed to be used as an internal standard for bioanalysis of B2M in mass-spectrometry. SILu Prot B2M is a monomer of 119 amino acids (including C-terminal polyhistidine and flag tags), with a molecular weight of ~14 kDa.
Suggested Quantitative Analysis Parameters
(MRM settings provided for three suggested peptides)

生化/生理作用

B2M is the light chain of the major histocompatibility class (MHC) I molecule expressed on the cell surface of all nucleated cells. Increased urinary B2M excretion has been observed to be an early marker of tubular injury in a number of settings, including nephrotoxicant exposure, cardiac surgery, and renal transplantation, preceding rises in serum creatinine by as many as 4−5 days. B2M may also serve as an early biomarker for AKI (Acute Kidney Injury).

序列

IQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDRDMDYKDDDDKGHHHHHHHHGGQ

外形

Supplied as a lyophilized powder containing phosphate buffered saline.

法律信息

SILu is a trademark of sigma-aldrich Co. LLC

基本信息

NACRESNA.12

产品性质

质量水平200
生物来源human
重组expressed in HEK 293 cells
测定≥98% (SDS-PAGE)
形式lyophilized powder
效能≥98% Heavy amino acids incorporation efficiency by MS
technique(s)mass spectrometry (MS): suitable
适用性suitable for mass spectrometry (standard)
UniProt登记号P61769
储存温度−20℃
Gene Informationhuman ... B2M(567)

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

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