产品说明
一般描述
SILu™Lite IL8 is a recombinant human protein expressed in human 293 cells. It is a mixture of the 3 main CXCL8 isoforms with the molecular weights, amino acid number and relative abundance as described in Table 1 of the product datasheet. SILu™Lite IL8 is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
生化/生理作用
Interleukin-8 (IL-8) is a member of the CXC chemokine subfamily and is produced by blood cells and many types of tissues. The measurement of IL-8 in voided urinary samples may have utility for urine-based detection of bladder cancer. Urinary IL-8 was a strong biomarker of stress under intensive and prolonged demands, both acutely and over time. IL-8 and cathepsin B levels were significantly elevated in melanoma patients, and more importantly, the combination of IL-8 and cathepsin B were also studied as a prognosis marker for melanoma mortality.
序列
EGAVLPRSAKELRCQCIKTYSKPFHPKFIKELRVIESGPHCANTEIIVKLSDGRELCLDPKENWVQRVVEKFLKRAENS
外形
Supplied as a lyophilized powder containing phosphate buffered saline.
法律信息
SILu is a trademark of sigma-aldrich Co. LLC
基本信息
| NACRES | NA.32 |
产品性质
| 重组 | expressed in HEK 293 cells |
| 质量水平 | 200 |
| 测定 | ≥95% (SDS-PAGE) |
| 形式 | lyophilized powder |
| 适用性 | suitable for mass spectrometry (internal calibrator) |
| UniProt登记号 | P10145 |
| 运输 | ambient |
| 储存温度 | −20℃ |
| Gene Information | human ... CXCL8(3576) |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
