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R-Spondin 4, Mouse, Recombinant

品牌
Sigma-Aldrich
货号
552095
包装型号
规格纯度
参考价格
7379.67 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Recombinant, mouse R-Spondin 4 consisting of amino acids 19-228 and expressed in Chinese Hamster Ovary cells. Able to induce activation of β-catenin response in a Luciferase assay using HEK293T human embryonic kidney cells. R-spondin 4 is useful as a positive modulator of Wnt/β signaling.

包装

25 μg in Glass bottle

生化/生理作用

ED₅₀ = 5-20 ng/ml in the presence of 10 ng/ml rmWnt-3a, as measured by induction of activation of β-catenin response in a Topflash Luciferase assay using HEK293T human embryonic kidney cells.

警告

Toxicity: Standard Handling (A)

外形

Lyophilized from 0.2 µm sterile-filtered PBS, NaCl, EDTA, BSA.

重悬

Reconstitute to 200 µg/ml in PBS.

其他说明

Hendrickx, M. and L. Leyns. 2008. Develop. Growth Differ.50, 229.
Ishii, Y., et al. 2008. J. Invest. Dermatol.128, 867.
Kim, K.A., et al. 2008. Mol. Biol. Cell19, 2588.
Binnerts, M.E., et al. 2007. Proc. Natl. Acad. Sci. USA104 14700.
Nam, J.S., et al. 2007. Gene Expr. Patterns7, 306.
Pemberton, T.J., et al. 2007. Dev. Dyn.236, 2245.
Bergmann, C., et al. 2006. Am. J. Hum. Genet.79, 1105.
Blaydon, D.C., et al. 2006. Nat. Genet.38, 1245.
Nam, J.S., et al. 2006. J. Biol. Chem.281, 13247.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

产品性质

测定≥95% (SDS-PAGE)
质量水平100
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
杂质<1.0 EU/μg protein Endotoxin
运输ambient
储存温度−20℃

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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