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Propargyl-PEG1-acid

品牌
Sigma-Aldrich
CAS
55683-37-9
货号
901567
包装型号
规格纯度
≥95%
参考价格
689.37 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

This is a crosslinker with an alkyne group on one end and a carboxyl group on the other end. The alkyne can be used to attach to an azide using copper-catalyzed click chemistry. The compound contains a single PEG unit to help improve solubility.
Propargyl-PEG1-acid is a heterobifunctional, PEGylated crosslinker featuring a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophillic PEG linker facilitates solubility in biological applications. Propargyl-PEG1-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.

法律信息

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

基本信息

经验(实验)分子式C6H8O3
分子量128.13
MDL编号MFCD10689189

产品性质

测定≥95%
形式liquid
储存温度−20℃
SMILES stringOC(CCOCC#C)=O
InChI1S/C6H8O3/c1-2-4-9-5-3-6(7)8/h1H,3-5H2,(H,7,8)
InChI keyGMFDYXLFHSFUHE-UHFFFAOYSA-N

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3

Sigma-Aldrich

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