产品说明
一般描述
A cell-permeable dipeptide that acts as a selective and reversible PPARγ antagonist (KD = ~ 8 µM). Shown to inhibit the agonist activity of Rosiglitazone (100 nM) in a dose-dependent manner (IC50 = 31.9 µM) in transfected COS-7 cells.
A cell-permeable dipeptide that acts as a selective and reversible PPARγ antagonist (KD ~8 µM). Shown to inhibit the agonist activity of Rosiglitazone (100 nM) in a dose-dependent manner (IC50 = 31.9 µM) in transfected COS-7 cells.
包装
50 mg in Plastic ampoule
Packaged under inert gas
生化/生理作用
Primary Target
PPARγ
Product does not compete with ATP.
Reversible: yes
Cell permeable: yes
kd = ~ 8 µM as PPARγ antagonist
警告
Toxicity: Standard Handling (A)
制备说明
Addition of a small amount of acid or base may be required for complete solubilization.
重悬
Following reconstitution aliquot freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
其他说明
Ye, F., et al. 2006. Chembiochem7, 74.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C16H19N3O5 |
| 分子量 | 333.34 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥97% (elemental analysis) |
| 形式 | solid |
| manufacturer/tradename | Calbiochem® |
| 储存条件 | OK to freeze protect from light |
| 颜色 | white |
| 溶解性 | water: 30 mg/mL |
| 运输 | ambient |
| 储存温度 | 2-8℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
