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Plasminogen

纤溶酶原

品牌
Roche
货号
10874477001
规格纯度
from human serum
参考价格
2594.63 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Plasminogen is a profibrinolysin from human serum. Plasminogen, the proenzyme of the fibrinolytically active enzyme plasmin, is a single chain glycoprotein. Various isoelectric forms exist and can be separated by means of isoelectric focusing (IEF). The lyophilizate is stabilized with bovine serum albumin (BSA).

应用

Plasminogen is used for the determination of the activity of plasminogen activators. The enzyme is a substrate for tissue plasminogen activator (t-PA) in the t-PA test and a reference substance for t-PA therapy. It is used as the in-process control in the production of t-PA.

特点和优势

Contents
Lyophilizate, stabilized with bovine serum albumin.

质量

Contaminants: <0.05% plasmin; the preparation does not contain 6-aminohexanoic acid

序列

Native plasminogen (glu-plasminogen) has a N-terminal glutamic acid group. Partial plasma proteolysis gives rise to a molecule with N-terminal lysine (lys-plasminogen). Cleavage with elastase results in val-plasminogen. The complete amino acid sequence contains 790 amino acids. Roche Applied Science supplies glu-plasminogen.

制备说明

Stabilizers: stabilized with BSA
Working solution: Solvent is recommended in 20 mM sodium phosphate buffer, pH 7.5, 100 mM NaCl.
Storage conditions (working solution): -15 to -25 ℃
A solution in 20 mM sodium phosphate buffer, pH ca. 7.5, 100 mM NaCl is stable for several months without loss of activity when stored at -15 to -25 ℃.
Note:
Plasminogen is susceptible to autolysis, which may result in activation. Contact with the skin or other contamination (e.g., by microorganisms), is therefore to be avoided.

储存及稳定性

Store at 2 to 8 ℃. (Store dry!)

其他说明

仅用于生命科学研究。不可用于诊断。

产品性质

质量水平100
形式lyophilized
specific activity~11 units/mg protein (activated with streptokinase at 37 ℃ and pH 7.4 with Chromozym PL as the substrate.)
分子量 90-94 kDa
包装pkg of 20 U
manufacturer/tradenameRoche
运输wet ice

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)does not flash
闪点(C)does not flash

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