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NF-kB Activation Inhibitor IV-CAS 139141-12-1-Calbiochem

品牌
Sigma-Aldrich
CAS
139141-12-1
货号
481412
规格纯度
The NF-kB Activation Inhibitor IV, also referenced under CAS 139141-12-1, controls the biological activity of NF-kB. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
参考价格
2671.25 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

A cell-permeable trans-stilbene Resveratrol (Cat. No. 554325) analog that exhibits much enhanced anti-inflammatory potency, but no anti-oxidant activity. Suppresses LPS-induced COX-2 mRNA expression in BV-2 cells (~46% inhibition at 150 nM) and Shown to be ~130-fold more potent than Resveratrol in inhibiting TNF-α-stimulated NF-κB reporter activity in 293T cells (IC50 = 150 nM).

包装

10 mg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Cell permeable: yes
Target IC50: 150 nM inhibiting TNF-α-stimulated NF-κB reporter activity in 293T cells.
Primary Target
NF-κB Activation
Product does not compete with ATP.
Reversible: no

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

其他说明

Heynekamp, J.J., et al. 2006. J. Med. Chem.49, 7182.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C15H13FO
分子量228.26

产品性质

质量水平100
测定≥98% (HPLC)
形式crystalline solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
protect from light
溶解性DMSO: 20 mg/mL
运输ambient
储存温度2-8℃

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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