产品说明
应用
N-Methylated pomalidomide is a ligand used as a negative control for pomalidomide (P0018) in the recruitment of the Cereblon (CRBN) protein for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology.
其他说明
Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation
Portal: Building PROTAC® Degraders for Targeted Protein Degradation
Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4
Targeted Protein Degradation by Small Molecules
Small-Molecule PROTACS: New Approaches to Protein Degradation
法律信息
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
基本信息
经验(实验)分子式 | C14H13N3O4 |
分子量 | 287.27 |
NACRES | NA.22 |
产品性质
质量水平 | 100 |
测定 | ≥98% |
形式 | powder or crystals |
运输 | wet ice |
储存温度 | 2-8℃ |
SMILES string | O=C(C(CC1)N(C2=O)C(C3=C2C=CC=C3N)=O)N(C)C1=O |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |