产品说明
一般描述
A cell-permeable morpholino-benzodioxol compound that inhibits MIF tautomerase activity (Ki and IC50 = 0.57 and 2.4 µM, respectively) via direct non-covalent MIF interaction (KD = 24.5 µM). RDR 03758 at 10 µM is shown to completely neutralize the overriding effect of 100 ng/ml MIF on the inhibition of LPS-stimulated TNF production by dexamethasone (Cat. No. 265005) in RAW 264.7 marcophage cultures.
包装
10 mg in Glass bottle
Packaged under inert gas
警告
Toxicity: Standard Handling (A)
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
其他说明
Ouertatani-Sakouhi, H., et al. 2010. J. Biol. Chem.285, 26581.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C19H18F3NO4 |
| 分子量 | 381.35 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥97% (HPLC) |
| 形式 | solid |
| manufacturer/tradename | Calbiochem® |
| 储存条件 | OK to freeze protect from light |
| 颜色 | cream |
| 溶解性 | DMSO: 50 mg/mL, clear, colorless |
| 运输 | ambient |
| 储存温度 | 2-8℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
