产品说明
应用
Fluorescence microscopy, fluorescent retinoid binding assay, fluorescence spectroscopy.
生化/生理作用
Strong ligand for retinoic acid receptor proteins
特点和优势
LightOx22 is a synthetic analogue of all-trans-retinoic acid (ATRA), that exhibits solvatochromatic fluorescence emission when excited with UV or 405 nm light. The compound is a strong ligand for the retinoic acid receptor proteins (RARs) and related cellular retinoic acid binding proteins (CRABPI/II) and can, therefore, be used as a replacement for ATRA in cellular assays involving retinoid signaling processes. LightOx22 can be utilised to study retinoid behaviour using fluorescence microscopy, employed in a competitive fluorometric ligand-binding assay for direct determination of the strength of binding of non-fluorescent retinoids to a protein target, and as a fluorophore in fluorescence spectroscopy.
其他说明
Chemical Equivalency 1ea=1mg
法律信息
LightOx is a trademark of LightOx Ltd.
基本信息
| 经验(实验)分子式 | C22H23NO2 |
| 分子量 | 333.42 |
产品性质
| 测定 | ≥95% (HPLC) |
| 形式 | powder |
| 储存温度 | 2-8℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
