产品说明
一般描述
A set of 52 compounds are arranged in 96-well format, one compound per well (250 μl at 10 mM in DMSO)
应用
Cardiotoxicity Ligand Set has been used in the cumulative drug dosage studies on engineered human induced pluripotent stem cell-derived cardiomyocyte (hiPS-CM) tissues.
生化/生理作用
Cardiotoxicity is an important cause for concern in drug development and appears to cut across therapeutic indications and drug classes. Several drugs have been removed from the market recently because of prolonging the QT interval or causing Torsades de Pointes (TdP).
The Cardiotoxicity Ligand Set features a wide variety of drugs including anti-arrhythmics, antihistamines, antibiotics, anticonvulsants, antidepressants and antipsychotics that are known to have cardiotoxic side-effects.
特点和优势
This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
SDFile provided to construct a database containing:
- Structure
- Primary Name
- Secondary Name
- Pharmacological Activity
- Product Number
- Rack Position
基本信息
| NACRES | NA.77 |
产品性质
| 运输 | dry ice |
| 储存温度 | −20℃ |
安全信息
| 象形图 |    |
| 警示用语： | Danger |
| 危险声明 | H302 - H350 - H360FD - H362 - H411 |
| 预防措施声明 | P202 - P263 - P264 - P273 - P301 + P312 - P308 + P313 |
| 危险分类 | Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 1A - Lact. - Repr. 1B |
| 储存分类代码 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
