产品说明
一般描述
The vasoactive intestinal peptide/pituitary adenylate cyclase activating peptide receptor 1 (VPAC1) is a member of a class II subfamily of G-protein-coupled receptors and has a high affinity for vasoactive intestinal peptide (VIP). VPAC1 has been associated with many different lung cancer cell lines. VPAC1 is thought to be activated by FXR and may contribute to the regulation of bile secretion to protect against gallstone disease. VPAC1 could be used to regulate VIPs and, in turn, inhibit breast cancer growth. VPAC1 has also been implicated in regulation of the anti-inflammatory effects of VIP.
特异性
This antibody recognizes VPAC1 at the cytoplasmic domain.
免疫原
KLH-conjugated linear peptide corresponding to the cytoplasmic domain of VPAC1.
Epitope: Cytoplasmic domain
应用
Research Sub Category
Hormones & Receptors
Immunohistochemistry Analysis: 1:500 dilution from a previous lot detected VPAC1 in ovarian carcinoma tissue.
Anti-VPAC1 Antibody detects level of VPAC1 & has been published & validated for use in IH(P) & WB.
Research Category
Neuroscience
质量
Evaluated by Western Blot in SK-OV-3 cell lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected VPAC1 on 10 µg of SK-OV-3 cell lysate.
目标描述
~52 kDa observed. Multiple molecular weights of VPAC1 may be due to glycosylation. (Fabre, C, et al. (1993). Peptides. 14:483-489.)
外形
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
SK-OV-3 cell lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 纯化方式 | affinity chromatography |
| species reactivity | mouse, rat, human |
| technique(s) | immunohistochemistry: suitable (paraffin) western blot: suitable |
| NCBI登记号 | NP_035833 |
| UniProt登记号 | P97751 |
| 运输 | wet ice |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
