Anti-Tbr1 Antibody

产品说明

一般描述

Tbr1 gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Tbr1, a putative transcription factor known to be expressed in post-mitotic neurons, has been found highly expressed in glutamatergic early-born cortical neurons. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region the Tbr1 derived protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase.

免疫原

Epitope: This antibody recognizes Tbr1 near the N-terminus.
KLH-conjugated linear peptide corresponding to mouse Tbr1 near the N-terminus.

应用

Immunohistochemistry Analysis: 1:400 dilution from a previous lot detected Tbr1 in mouse cerebellum tissue.
Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience
Anti-Tbr1 Antibody detects level of Tbr1 & has been published & validated for use in IH(P).

质量

Evaluated by Immunohistochemistry in mouse frontal cortex tissue.

Immunohistochemistry Analysis: 1:400 dilution of this antibody detected Tbr1 in mouse frontal cortex tissue.

目标描述

74kDa calculated

外形

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
Mouse frontal cortex tissue

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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