产品说明
免疫原
Immunogen Sequence: GI # 4506007, sequence 1-323
Recombinant protein phosphatase 1, catalytic subunit, gamma isoform
应用
Anti-PPP1CC antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
生化/生理作用
Serine/threonine-protein phosphatase PP1-γ catalytic subunit is an enzyme encoded by the PPP1CC gene in humans. A novel phosphatidic acid (PA) binding region on PP1c-γ is identified that contains a unique loop-strand structural fold responsible for the interaction with PA. PP1c γ may function as a mediator of PA action in cells. There may be an existence of a specific high affinity PA-binding domain on the enzyme. Its overexpression promotes vascular smooth muscle cell survival by interfering with JNK1 and p53 phosphorylation cascades involved in apoptosis.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | chicken |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| species reactivity | human, rat, mouse |
| manufacturer/tradename | Genway 15-288-22549 |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_002701.1 |
| UniProt登记号 | P36873 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... PPP1CC(5501) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
