Anti-Melanin Concentrating Hormone Receptor Type 2 Antibody, intracellular, CT

产品说明

一般描述

Melanin Concentrating Hormone Receptor type 2 (MCH-R2) is a G-protein coupled receptor with seven transmembrane domains. MCH-R2 is 340 amino acids in length (approximately 39 kDa) and shares approximately 38% amino acid identity with MCH-R1. Like MCH-R1, it binds MCH with high affinity. However, reports indicate that signaling through this receptor is pertussis insensitive, contrary to MCH-R1. Expression of MCH-R2 mRNA is restricted to several regions of the brain, including the arcuate nucleus and the ventral medial hypothalamous (Sailer, 2001).

特异性

Human Melanin Concentrating Hormone Receptor Type 2 (MCH-R2). The antibody has been used to stain tissues from rat and mouse as well as human.

免疫原

Epitope: intracellular, C-terminus
Synthetic 16 amino acid peptide corresponding to the intracellular carboxy-terminus of human MHC-R2.

应用

Research Category
Neuroscience
Research Sub Category
CNS Control of Metabolism

Hormones & Receptors
Immunohistochemistry: 1 μg/mL on brain cryostat sections. The antibody stains extensively through the brain and is particularly striking in the ganglionic layer of the cerebellum.

Optimal working dilutions must be determined by end user.
This Anti-Melanin Concentrating Hormone Receptor Type 2 Antibody, intracellular, C-terminus is validated for use in IH for the detection of Melanin Concentrating Hormone Receptor Type 2.

外形

Affinity purified immunoglobulin in PBS, pH 7.2 containing 0.1% sodium azide.

储存及稳定性

Maintain frozen at -20°C in undiluted aliquots for up to 6 months after date of receipt. The antibody can also be diluted 1:1 with glycerol (ACS grade or better) for added stability. Avoid repeated freeze/thaw cycles.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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