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Anti-Integrin alpha-11 Antibody

品牌
Sigma-Aldrich
货号
AB6031
规格纯度
from rabbit, purified by affinity chromatography
参考价格
6022.61 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Integrin alpha-11 (ITGA11) belongs to a family of cell adhesion molecules, which consist of noncovalent associated alpha-beta heterodimers, and is shown to be overexpressed in the stroma of human non-small-cell lung carcinomas (hNSCLCs). Upon dimerization, this protein is thought to enhance tumorgenicity of hNSCLCs by interacting with matrix collagen and stromal fibroblasts. Progesterone is shown to increase the expression of ITGA11 through mid-gestation and decrease thereafter in Sprague-Dawley rats. It is further indicated that MAPK signaling is associated with the regulation of these integrins.

免疫原

Linear peptide corresponding to human Integrin alpha-11.

应用

Research Category
Cell Structure
Research Sub Category
Integrins
Anti-Integrin alpha-11 Antibody is an antibody against Integrin alpha-11 for use in WB.

质量

Evaluated by Western Blot in HeLa cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected Integrin alpha-11 in 10 µg of non-boiled & non-B-ME HeLa cell lysate.

目标描述

~135 kDa observed.
The high molecular weight band seen in a HeLa (non boiled) cell lysate is the integrin complex. The band at ~75-80 kDa is thought to be a denatured form of integrin.

外形

Purified rabbit polyclonal containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
Non-boiled & non-B-ME HeLa cell lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

生物来源rabbit
质量水平100
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
纯化方式affinity chromatography
species reactivityhuman
species reactivity (predicted by homology)rat (based on 100% sequence homology), mouse (based on 100% sequence homology)
technique(s)western blot: suitable
NCBI登记号NP_001004439
UniProt登记号Q9UKX5
运输wet ice

安全信息

储存分类代码10 - Combustible liquids

Sigma-Aldrich

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