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Anti-APAF1 antibody produced in chicken

品牌
Sigma-Aldrich
货号
GW21169
规格纯度
affinity isolated antibody, buffered aqueous solution
参考价格
4731.57 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

免疫原

Immunogen Sequence: GI # 32483361, sequence 307-388
Recombinant apoptotic protease activating factor isoform d

应用

Anti-APAF1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

Apoptotic protease activating factor 1 is a human homolog of C. elegans CED-4 gene and is a key regulator gene of apoptosis. It acts as a central component of the intrinsic pathway of apoptosis. Loss of APAF-1 expression is involved with chemorefractory malignant melanoma and neuronal cell differentiation. Over expression of this gene is related to an undifferentiated state in the testicular germ cell tumor (TGCT) pathway and is involved in carcinogenesis of germ cell tumors. APAF-1, when bound to cytochrome c, may trigger the activation of caspase-3 leading to apoptosis.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide.

基本信息

MDL编号MFCD02095846
NACRESNA.41

产品性质

生物来源chicken
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
species reactivityhuman, mouse
manufacturer/tradenameGenway 15-288-21169
technique(s)western blot: suitable
NCBI登记号NP_863658.1
UniProt登记号O14727
运输wet ice
储存温度−20℃
Gene Informationhuman ... APAF1(317)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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