产品说明
一般描述
Potent Cl– channel blocker (IC50 = 100 nM-100 µM), depending on channel subtype and assay method. Inhibits cyclooxygenase (IC50 = 8 µM).
Potent Cl- channel blocker (IC50 = 100 nM-100 µM), depending on channel subtype and assay method. Inhibits cyclooxygenase (IC50 = 8 µM).
包装
10 mg in Plastic ampoule
生化/生理作用
Product does not compete with ATP.
Reversible: no
Primary Target
Cl⁻ channel blocker
Target IC50: 100 nM-100 µM as Cl-channel blocker
Cell permeable: no
警告
Toxicity: Standard Handling (A)
其他说明
Illek, B., et al. 1992. Am. J. Physiol.263, C644.
Kirk, K., et al. 1992. J. Biol. Chem.267, 23475.
Breuer, W., et al. 1989. Biochem. Biophys. Res. Commun.163, 398.
Wangermann, P., et al. 1986. Pflugers Arch.407, S128.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C16H16N2O4 |
| 分子量 | 300.31 |
| MDL编号 | MFCD00153851 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | solid |
| manufacturer/tradename | Calbiochem® |
| 储存条件 | OK to freeze |
| 颜色 | yellow |
| 溶解性 | DMSO: 5 mg/mL warm ethanol: soluble |
| 运输 | ambient |
| 储存温度 | 10-30℃ |
| InChI | 1S/C16H16N2O4/c19-16(20)14-11-13(18(21)22)8-9-15(14)17-10-4-7-12-5-2-1-3-6-12/h1-3,5-6,8-9,11,17H,4,7,10H2,(H,19,20) |
| InChI key | WBSMIPAMAXNXFS-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
