产品说明
应用
2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and hydroxyl synthetic handle. When appended to a ligand or pharmacophore through its hydroxyl linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.
其他说明
Technology Spotlight: Trifunctional Probe Building Blocks
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In Situ Proteome Profiling and Bioimaging Applications of Small-Molecule Affinity-Based Probes Derived From DOT1L Inhibitors
Reversible inhibitors arrest ClpP in a defined conformational state that can be revoked by ClpX association
Design and Synthesis of Minimalist Terminal Alkyne-Containing Diazirine Photo-Crosslinkers and Their Incorporation into Kinase Inhibitors for Cell- and Tissue-Based Proteome Profiling
基本信息
| 经验(实验)分子式 | C7H10N2O |
| 分子量 | 138.17 |
| MDL编号 | MFCD29918290 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥95% |
| 形式 | liquid |
| 密度 | 1.08 g/mL |
| 储存温度 | −20℃ |
| SMILES string | OCCC1(N=N1)CCC#C |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
