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15-PGDH Inhibitor-Calbiochem

品牌
Sigma-Aldrich
货号
100073
规格纯度
The 15-PGDH Inhibitor controls the biological activity of 15-PGDH. This small molecule/inhibitor is primarily used for Membrane applications.
参考价格
2340.22 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

A cell-permeable, thiazolidinedione derivative that acts as a 15-hydroxyprostaglandin dehydrogenase (15-PGDH) inhibitor (IC50 = 25 nM). It is shown to increase PGE2 levels in IL-1β-stimulated A549 cells, dose-dependently, in the range of 0–20 µM, and elicits cochlear blood flow (CBF) increase by 15% and 55% when applied intravenously to 250 g guinea pigs at 10 µg and 20 µg respectively.

包装

10 mg in Glass bottle
Packaged under inert gas

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Wu, Y., et al. 2011. J. Med. Chem.54, 5260.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C19H23NO4S
分子量361.46

产品性质

质量水平100
测定≥99% (HPLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
protect from light
颜色 yellow
溶解性DMSO: 100 mg/mL, clear, pale yellow
运输ambient
储存温度2-8℃
SMILES stringO=C(NC/1=O)SC1=C/C2=CC=C(OCCC3CCCCC3)C(OC)=C2

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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