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Thiol-poly(ethylene glycol)-b-poly(ε-caprolactone)

品牌
Sigma-Aldrich
货号
901708
规格纯度
PEG average Mn 5000, PCL average Mn 5000
参考价格
4792.42 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

Thiol-poly(ethylene glycol)-b-poly(ε-caprolactone) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PCL block. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). Additionally, well-defined nanoparticles with tunable size and properties can be prepared by altering the molecular weight ratios between hydrophilic and hydrophobic blocks, as well as by controlling formulation parameters. The thiol functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.

基本信息

线性分子式C5H10S2O[C2H4O]n[C6H10O2]mH
NACRESNA.23

产品性质

形式powder or solid
分子量PCL average Mn 5000
PEG average Mn 5000
颜色 white to off-white
PDI≤1.3 (By GPC)
储存温度−20℃

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P301 + P312 + P330
危险分类Acute Tox. 4 Oral
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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