产品介绍:
产品说明
一般描述
Propionyl-L-carnitine (PLC) is a short-chain fatty acid ester derivative of carnitine.
应用
Propionyl-L-carnitine has been used as a standard in liquid chromatography-tandem mass spectrometry (LC-MS/MS).
生化/生理作用
Propionyl-L-carnitine (PLC) plays a key role in lipid and carbohydrate metabolism. It provides substrates to the ischemic muscle for energy production and ATP generation. PLC has the potential to treat severe peripheral arterial disease and chronic heart failure. It is present in high abundance in the urine of patients with methylmalonyl-CoA mutase (MUT) deficiency, together with methylmalonic acid. MUT is a mitochondrial enzyme that catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA.
基本信息
经验(实验)分子式 | C10H19NO4 |
分子量 | 217.26 |
MDL编号 | MFCD00870024 |
PubChem化学物质编号 | 329756246 |
NACRES | NA.26 |
产品性质
质量水平 | 100 |
测定 | ≥94.0% (HPLC) |
形式 | powder or crystals |
旋光性 | [α]/D -23±3°, c = 1 in H2O |
technique(s) | LC/MS: suitable |
杂质 | ≤10% water (calcd. from elemental analysis) |
颜色 | white to off-white |
储存温度 | 2-8℃ |
SMILES string | [O-]C(C[C@@H](OC(CC)=O)C[N+](C)(C)C)=O |
InChI | 1S/C10H19NO4/c1-5-10(14)15-8(6-9(12)13)7-11(2,3)4/h8H,5-7H2,1-4H3/t8-/m1/s1 |
InChI key | UFAHZIUFPNSHSL-MRVPVSSYSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |