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Poly(ethylene glycol) bis(2-pyridyl KAT)

品牌
Sigma-Aldrich
货号
901635
规格纯度
PEG average Mn 10,000
参考价格
3905.55 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Poly(ethylene glycol) bis(2-pyridyl KAT) is a homobifunctional PEG featuring terminal potassium acyltrifluoroborate reactive groups for facile, rapid functionalization. Potassium acyltrifluoroborates (KATs) are stable functional groups that undergo rapid amide-forming ligations with hydroxylamines in aqueous media, in the presence of unprotected functional groups. In addition to its compatibility, these reactions proceed relatively quickly, lending to their use with sensitive biological reagents. This conjugation reaction offers a new approach to the synthesis of complex molecules without the complication of side reactions, such protein-polymer conjugates. KATs also undergo amide or imide-forming ligations in acidic conditions when reacted with primary amines or amides, respectively, as an alternative to classical acylation chemistry. Poly(ethylene glycol) bis(2-pyridyl KAT)s have been recently used in the rapid PEGylation and dimerization of expressed, folded protiens in near equimolar conditions, demonstrating the potential for these materials in a wide variety of drug delivery applications.

基本信息

线性分子式(C6H3BF3KNO)O[CH2CH2O]nCH2CH2O(C6H3BF3KNO)
NACRESNA.23

产品性质

形式powder or solid
分子量PEG average Mn 10,000
PEG ~10,000 Da
颜色 off-white to pale yellow
储存温度2-8℃

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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