产品说明
一般描述
Epidermal growth-factor receptor (EGF-R) conserved sequence which is identical to v-erbB (95-102). An N-terminal myristoylated membrane-permeable, reversible, and substrate competitive inhibitor that inhibits protein kinase C (IC50 = 5 µM) in intact cells.
Epidermal growth-factor receptor (EGF-R) conserved sequence which is identical to v-ErbB (95-102). An N-terminal myristoylated membrane-permeable, reversible, and substrate competitive inhibitor of protein kinase C (IC50 = 5 µM).
包装
500 μg in Plastic ampoule
Yes
生化/生理作用
Product does not compete with ATP.
Target IC50: 5 µM against protein kinase C
Reversible: yes
Primary Target
PKC
Cell permeable: yes
警告
Toxicity: Standard Handling (A)
序列
Myr-N-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu-OH
外形
Supplied as a trifluoroacetate salt.
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
其他说明
Ward, N.E., and O’Brian, C.A. 1993. Biochemistry32, 11903.
O’Brian, C.A., et al. 1991. Invest. New Drugs 9, 169.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
经验(实验)分子式 | C60H117N21O11 |
分子量 | 1308.71 |
产品性质
质量水平 | 100 |
测定 | ≥97% (HPLC) |
形式 | lyophilized solid |
manufacturer/tradename | Calbiochem® |
储存条件 | OK to freeze desiccated |
溶解性 | water: 5 mg/mL |
运输 | ambient |
储存温度 | −20℃ |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |