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Osteocalcin, Bovine Bone

品牌
Sigma-Aldrich
货号
499050
包装型号
规格纯度
参考价格
6369.72 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Single chain vitamin K-dependent protein produced by osteoblasts. Osteocalcin purified from bovine bone. Binds to phospholipid vesicles in the presence of Ca2+ (Kd = 6 µM). Also binds hydroxylapatite. Possible role in bone mineralization, bone resorption, and bone formation. Note: Gla corresponds to γ-carboxyglutamic acid.
Single chain vitamin K-dependent protein produced by osteoblasts. Osteocalcin purified from bovine bone. Binds to phospholipid vesicles in the presence of Ca2+ (Kd = 6 µM). Also binds hydroxylapatite. A good marker of bone turnover. May play a role in bone mineralization, bone resorption, and bone formation.

包装

100 μg in Plastic ampoule

警告

Toxicity: Standard Handling (A)

序列

H-Tyr-Leu-Asp-His-Trp-Leu-Gly-Ala-Pro-Ala-Pro-Tyr-Pro-Asp-Pro-Leu-Gla-Pro-Lys-Arg-Gla-Val-Cys²³-Gla-Leu-Asn-Pro-Asp-Cys²⁹-Asp-Glu-Leu-Ala-Asp-His-Ile-Gly-Phe-Gln-Glu-Ala-Tyr-Arg-Arg-Phe-Tyr-Gly-Pro-Val-OH (disulfide bond: 23 → 29)

外形

In 75 mM NaCl, 10 mM sodium phosphate buffer, pH 7.4.

重悬

Following initial thaw, aliquot and freeze (-20°C).

其他说明

Carter, S.D., et al. 1996. J. Anim. Sci. 74, 2719.
Watson, K.E., et al. 1994. J. Clin. Invest.93, 2106.
Tracy, R.P., et al. 1990. J. Bone Min. Res.5, 451.
Gendreau, M.A., et al. 1989. J. Biol. Chem.264, 6972.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C263H372N66O82S2
分子量5834.29

产品性质

质量水平100
测定≥98% (SDS-PAGE)
形式liquid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
avoid repeated freeze/thaw cycles
pI 4.0 - 4.5
运输wet ice
储存温度−20℃

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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