产品介绍：
产品说明
应用
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8a,9S)-6′-methoxy-9-cinchonanyl]thiourea is a bifunctional cinchona organocatalyst, which can be used to synthesize:
- Stereoselective diaryl(nitro)butanone via enantioselective Michael addition of nitromethane to chalcones.
- Enantioselective β-amino acids via asymmetric Mannich reaction of malonates with aryl and alkyl imines.
- The synthesis of 3-indolylmethanamines by the reaction of indoles with imines via asymmetric Friedel-Crafts reaction.
- The enantioselective conjugate addition of active methylene compounds to enones to obtain the corresponding addition products.
包装
250 mg in glass bottle
Bottomless glass bottle. Contents are inside inserted fused cone.
基本信息
| 经验(实验)分子式 | C29H28F6N4OS |
| 分子量 | 594.61 |
| MDL编号 | MFCD16875670 |
| PubChem化学物质编号 | 329761344 |
| NACRES | NA.22 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥89.0% 90% |
| SMILES string | COc1ccc2nccc([C@H](NC(=S)Nc3cc(cc(c3)C(F)(F)F)C(F)(F)F)C4CC5CCN4C[C@@H]5C=C)c2c1 |
| InChI | 1S/C29H28F6N4OS/c1-3-16-15-39-9-7-17(16)10-25(39)26(22-6-8-36-24-5-4-21(40-2)14-23(22)24)38-27(41)37-20-12-18(28(30,31)32)11-19(13-20)29(33,34)35/h3-6,8,11-14,16-17,25-26H,1,7,9-10,15H2,2H3,(H2,37,38,41)/t16-,17-,25-,26-/m0/s1 |
| InChI key | IQMKPBFOEWWDIQ-FRSFCCSCSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Danger |
| 危险声明 | H301 |
| 预防措施声明 | P301 + P310 |
| 危险分类 | Acute Tox. 3 Oral |
| 储存分类代码 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
