产品说明
一般描述
The MystiCq® microRNA qPCR Assay Primer is an integral part of the MystiCq microRNA qPCR Assay System. It has been designed to target specific microRNAs with the MystiCq Universal PCR primer and the MystiCq® microRNA SYBR® Green qPCR ReadyMix™ on cDNA templates generated by the MystiCq microRNA cDNA Synthesis Mix kit.
生化/生理作用
The microRNA hsa-miR-506 is involved in modulating cell differentiation, migration and proliferation. It has anti-oncogenic properties. miR-506 is localized on human chromosome Xq27.3. It inhibits epithelial-to-mesenchymal transition in cancer cells. miR-506 targets Pim-3 proto-oncogene (PIM3) and suppresses cell proliferation in pancreatic cancer.
特点和优势
- Proprietary design features of assay primers allow for specificity towards mature microRNAs vs. precursor-microRNAs
- Extensive design and testing of oligo-dT adapter primer to incorporate complementary Universal PCR Primer sequence
- No self-complementarity or primer dimer artifacts with the Universal PCR Primer
- Optimized primer Tm designed to match the Universal PCR Primer
- Universal cycling conditions ensures robust amplification for all assays in profiling experiments
- Optimized PCR product Tm (75-78° C)
其他说明
Formerly hsa-miR-506.
法律信息
MystiCq is a registered trademark of Qiagen Beverly Inc.
ReadyMix is a trademark of sigma-aldrich Co. LLC
SYBR is a registered trademark of Life Technologies
基本信息
| miRNA ID | hsa-miR-506-3p Sanger Database |
产品性质
| 形式 | liquid |
| 浓度 | 10 mg/mL |
| 成熟序列 | UAAGGCACCCUUCUGAGUAGA |
| mp | ~76.5 ℃ |
| Sanger mature/minor 登记号 | MIMAT0002878 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... MIR506(574511) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
