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DIDS, Disodium Salt-CAS 53005-05-3-Calbiochem

二钠盐-CAS 53005-05-3-Calbiochem

品牌
Sigma-Aldrich
CAS
53005-05-3
货号
309795
规格纯度
Binds covalently and irreversibly to the outer surface of human erythrocyte membranes.
参考价格
2425.45 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Binds covalently and irreversibly to the outer surface of human erythrocyte membranes. Inhibits ATP transport into endoplasmic reticulum vesicles. Anion transport inhibitor that inhibits Cl uptake (IC50 = 150 nM) in neuroblastoma cells. Has anti-ulcerous properties.
Binds covalently and irreversibly to the outer surface of human erythrocyte membrane proteins. Inhibits ATP transport into the endoplasmic reticulum vesicles. Anion transport inhibitor that inhibits Cl- uptake (IC50 = 150 nM) in neuroblastoma cells. Has antiulcerous activity.

包装

250 mg in Plastic ampoule

生化/生理作用

Primary Target
Cl- uptake
Target IC50: 150 nM inhibiting Cl- uptake in neuroblastoma cells
Product does not compete with ATP.
Reversible: no
Cell permeable: no

警告

Toxicity: Irritant (B)

其他说明

Bettendorff, L., et al. 1995. Biochem. Biophys. Res. Commun. 207, 375.
Horie, S., et al. 1993. Res. Commun. Chem. Pathol. Pharmacol. 79, 117.
Mayinger, P., and Meyer, D.I. 1993. EMBO J. 12, 659.
Catantchik, Z.I., and Rothstein, A. 1974. J. Membr. Biol.15, 207.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C16H8N2O6S4 · 2Na
分子量498.48

产品性质

质量水平100
测定≥85% (TLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
desiccated
protect from light
颜色 yellow
溶解性water: 0.5%
运输ambient
储存温度−20℃
InChI1S/C16H10N2O6S4/c19-27(20,21)15-7-13(17-9-25)5-3-11(15)1-2-12-4-6-14(18-10-26)8-16(12)28(22,23)24/h1-8H,(H,19,20,21)(H,22,23,24)/b2-1+
InChI keyYSCNMFDFYJUPEF-OWOJBTEDSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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