Complement C3a des-Arg, Human

产品说明

一般描述

Native, human des-Arg C3 complement component. Single chain, 76 amino acid peptide. Once the C3a peptide has been produced in human plasma or serum, it is rapidly converted to C3a des-Arg upon removal of the C-terminal arginine by endogenous serum carboxypeptidase N. This enzymatic process is considered to be a major mechanism for controlling C3a function in vivo because C3a des-Arg has <1% of the biological activity expressed by the C3a peptide. Therefore, C3a des-Arg can serve as a negative control molecule in experiments involved with the biological activities of the intact C3a anaphylatoxin peptide.

包装

50 μg in Plastic ampoule
Please refer to vial label for lot-specific concentration.

生化/生理作用

Ileum contraction assay: negative

警告

Toxicity: Standard Handling (A)

外形

In PBS, pH 7.2.

制备说明

Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

重悬

Following initial thaw, aliquot and freeze (-70°C).

其他说明

Kajita, T. and Hugli, T.E. 1991. Am. J. Pathol. 138, 1359.
Bokish, V.A. and Muller-Eberhard, H.J. 1970. J. Clin. Invest.49, 2427.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

产品性质

安全信息