产品说明
应用
C5 Lenalidomide is a derivative of the Cereblon (CRBN)-binding ligand lenalidomide, which possesses an amine at the C4 position. C5 Lenalidomide can be used to bind the CRBN E3 ubiquitin ligase in targeted protein degradation research or in the synthesis of protein degraders with a C5 exit vector. Learn more about proteolysis-targeting chimeras (PROTACs) and the building blocks to design them in our Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation
其他说明
Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation
Portal: Building PROTAC® Degraders for Targeted Protein Degradation
Amino-substituted thalidomide analogs: potent inhibitors of TNF-alpha production
Targeted Protein Degradation by Small Molecules
法律信息
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
基本信息
| 经验(实验)分子式 | C13H13N3O3 |
| 分子量 | 259.26 |
| MDL编号 | MFCD31692701 |
产品性质
| 测定 | ≥95% |
| 形式 | powder |
| 储存温度 | 2-8℃ |
| SMILES string | NC1=CC=C2C(CN(C3CCC(NC3=O)=O)C2=O)=C1 NC1=CC=C2C(CN(C3CCC(NC3=O)=O)C2=O)=C1 |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H361d - H373 |
| 预防措施声明 | P201 - P308 + P313 |
| 危险分类 | Repr. 2 - STOT RE 2 |
| 靶器官 | Blood |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
