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Anti-SerPINE1 (AB2) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV47470
规格纯度
affinity isolated antibody
参考价格
6262.8 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

SerPINE1 is a serine proteinase inhibitor that blocks fibrinolys by inhibiting tissue plasminogen activator (tPA) and urokinase (uPA). Genetic variations in SERPINE1 have been linked to pre-eclampsia (PE). Studies have reported that targeting SERPINE1 (PAI-1) expression in Alzheimer′s disease may have therapeutic implications. Moreover, MiR-34c regulates SERPINE1 expression in emphysema.
Rabbit Anti-SerPINE1 antibody recognizes human, mouse, rat, zebrafish, bovine, pig, chicken, and canine SERPINE1.

免疫原

Synthetic peptide directed towards the C terminal region of human SERPINE1

应用

Rabbit Anti-SerPINE1 antibody is suitable for western blot applications at a concentration of 0.5 μg/ml.

生化/生理作用

SERPINE1 acts as ′bait′ for tissue plasminogen activator, urokinase, and protein C. Its rapid interaction with TPA may function as a major control point in the regulation of fibrinolysis.

序列

Synthetic peptide located within the following region: VNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVM

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD00164749
NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 43 kDa
species reactivityrat, pig, bovine, human, horse, sheep, dog, rabbit
浓度0.5 mg - 1 mg/mL
technique(s)western blot: suitable
NCBI登记号NP_000593
UniProt登记号P05121
运输wet ice
储存温度−20℃
Gene Informationhuman ... SERPINE1(5054)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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