产品说明
一般描述
PAWR is a transcriptional repressor that has a leucine zipper domain. Genetic variations in PAWR have been linked to major depressive disorder (MDD) and schizophrenia.
Rabbit Anti-PAWR (AB2) antibody recognizes human, mouse, and rat PAWR.
免疫原
Synthetic peptide directed towards the middle region of human PAWR
应用
Rabbit Anti-PAWR (AB2) can be used for western blot applications at a concentration of 0.5-1.0μg/ml. It can also be used for IHC at 4-8μg/ml.
生化/生理作用
The tumor suppressor WT1 represses and activates transcription. Anti-Prostate Apoptosis Response Protein Par-4 (PAWR) is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.
序列
Synthetic peptide located within the following region: SYLLQEPPRTVSGRYKSTTSVSEEDVSSRYSRTDRSGFPRYNRDANVSGT
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 37 kDa |
| species reactivity | dog, human |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI登记号 | NP_002574 |
| UniProt登记号 | O75796 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... PAWR(5074) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
