Anti-p16 (Ab-1) Mouse mAb (DCS-50.1/H4)

产品说明

一般描述

This Anti-p16 (Ab-1) Mouse mAb (DCS-50.1/H4) is validated for use in Immunoblotting for the detection of p16 (Ab-1).
Purified mouse monoclonal antibody generated by immunizing BALB/c mice with the specified immunogen and fusing splenocytes with NS-2 mouse myeloma cells. Recognizes the ~16 kDa p16 protein.
Recognizes the ~16 kDa p16 protein in Saos-2 cells and bladder tissue. Sold under license of U.S. Patent 6,482,929. Sold under license of U.S. Patent 5,843,756, 6,090,578, and corresponding patents.

免疫原

Human
recombinant, human p16

包装

100 μg in Plastic ampoule
Please refer to vial label for lot-specific concentration.

应用

Immunoblotting (0.5-5 µg/ml, see application references)

警告

Toxicity: Standard Handling (A)

外形

In 0.05 M sodium phosphate buffer, 0.2% gelatin pH 7.5.

分析说明

Negative Control
U2OS cells
Positive Control
Saos-2 cells or bladder tissue

其他说明

Does not cross-react with the closely related p15 protein. Antibody should be titrated for optimal results in individual systems.
Koh, J., et al. 1995. Nature375, 506.
Lukas, J., et al. 1995. Nature375, 503.
Cheng, J.Q., et al. 1994. Cancer Res.54, 5547.
Jen, J., et al. 1994. Cancer Res.54, 6353.
Kamb, A., et al. 1994 Science264, 436.
Nobori, T., Miura, K., et al. 1994. Nature368, 753.
Okamoto, A., Demetrick, D.J., et al. 1994. Proc. Natl. Acad. Sci. USA91, 11045.
Serrano, M., et al. 1993. Nature366 704.

法律信息

Sold under license of U.S. Patents 5,843,756, 6,090,578 and corresponding patents.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

产品性质

安全信息