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Anti-NEUROD2 (AB1) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV38741
规格纯度
affinity isolated antibody
参考价格
6305.78 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

免疫原

Synthetic peptide directed towards the C terminal region of human NEUROD2

生化/生理作用

NEUROD2 (Neurogenic differentiation 2) is a key transcription factor of the neuron-specific promoters such as GAP-43. It induces neurogenic differentiation by inhibiting RE1-Silencing Transcription Factor-mediated gene expression. NEUROD2 expression is critical for the development of amygdala, hippocampal mossy fiber synapses and for emotional learning.
NEUROD2 is a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of NEUROD2 can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. NEUROD2 can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates.This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. The product of the human gene can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates.

序列

Synthetic peptide located within the following region: PGSRPTGHGLVFGSSAVRGGVHSENLLSYDMHLHHDRGPMYEELNAFFHN

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 41 kDa
species reactivityrat, dog, mouse, rabbit, human, horse, guinea pig, bovine
浓度0.5 mg - 1 mg/mL
technique(s)western blot: suitable
NCBI登记号NP_006151
UniProt登记号Q15784
运输wet ice
储存温度−20℃
Gene Informationhuman ... NEUROD2(4761)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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